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Assay Detail

CHEMBL749552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity for Nicotinic acetylcholine receptor alpha7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL4980)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Holladay MW, Dart MJ, Lynch JK.
J Med Chem (1997) 40 : 4169 -4194
PubMed 9435889 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.44 4.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL132966 RIVANICLINE 2.0 1 4.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL132966 RIVANICLINE Ki = 36000.0 nM 4.44