Assay Detail
Binding
CHEMBL750041
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Binding affinity to displace 0.4 nM of [3H]- gallopamil in rat myocardial membranes
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Myocardium |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Studies on Ca2+ channel antagonists. A 2-diazo-3,3,3-trifluoropropionamide derivative related to verapamil as a potential photoaffinity probe.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.62 | 7.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51149 | GALLOPAMIL | 2.0 | 2 | 7.81 |
| CHEMBL355473 | — | — | 2 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51149 | GALLOPAMIL | Ki | = | 15.5 | nM | 7.81 |
| CHEMBL51149 | GALLOPAMIL | Ki | = | 15.5 | nM | 7.81 |
| CHEMBL355473 | — | Ki | = | 37.6 | nM | 7.42 |
| CHEMBL355473 | — | Ki | = | 37.6 | nM | 7.42 |