Assay Detail
Binding
CHEMBL750111
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Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cercopithecidae |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
3-Deoxyclocinnamox: the first high-affinity, nonpeptide mu-opioid antagonist lacking a phenolic hydroxyl group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.58 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL386492 | CLOCINNAMOX | — | 1 | 8.80 |
| CHEMBL386272 | — | — | 1 | 8.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL386492 | CLOCINNAMOX | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL386272 | — | Ki | = | 4.5 | nM | 8.35 |