Assay Detail
Binding
CHEMBL750117
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Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal Membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and opioid binding properties of 2-chloroacrylamido derivatives of 7,8-dihydromorphinans
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.53 | 9.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289426 | — | — | 1 | 9.28 |
| CHEMBL41366 | — | — | 1 | 7.35 |
| CHEMBL290616 | — | — | 1 | 6.75 |
| CHEMBL288178 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289426 | — | IC50 | = | 0.53 | nM | 9.28 |
| CHEMBL41366 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL290616 | — | IC50 | = | 178.0 | nM | 6.75 |
| CHEMBL288178 | — | IC50 | = | 177.0 | nM | 6.75 |