Assay Detail
Binding
CHEMBL750200
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Compound was tested for inhibition of osteoclast vacuolar ATPase derived from chicken medullary bone
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Solid phase synthesis of diamides as potential bone resorption inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.42 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290814 | BAFILOMYCIN A1 | — | 1 | 7.52 |
| CHEMBL449696 | — | — | 1 | 7.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290814 | BAFILOMYCIN A1 | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL449696 | — | IC50 | = | 49.0 | nM | 7.31 |