Assay Detail
Functional
CHEMBL750346
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity in theOpioid receptor kappa 1 -mediated [35S]GTP-gamma-S, binding assay against 50 nM U-50,488
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of dynorphin a analogues modified in the address sequence.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.36 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413729 | — | — | 1 | 6.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413729 | — | IC50 | = | 440.0 | nM | 6.36 |