Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL750464

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for in vitro inhibition of myenteric plexus, guinea pig at NMDA receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Glutamate [NMDA] receptor (CHEMBL2094124)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
Leeson PD, Iversen LL.
J Med Chem (1994) 37 : 4053 -4067
PubMed 7990104 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL131272 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL131272 IC50 = 5000.0 nM 5.30