Assay Detail
Binding
CHEMBL750765
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Compound was evaluated for its inhibitory activity against Y2 receptor of rabbit kidney membrane
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel Y2-selective, reduced-size agonists of neuropeptide Y
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.75 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL438945 | HUMAN NEUROPEPTIDE Y | 1.0 | 1 | 9.30 |
| CHEMBL268351 | — | — | 1 | 8.10 |
| CHEMBL415176 | — | — | 1 | 7.80 |
| CHEMBL414482 | — | — | 1 | 7.75 |
| CHEMBL266077 | — | — | 1 | 6.80 |
| CHEMBL438580 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL438945 | HUMAN NEUROPEPTIDE Y | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL268351 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL415176 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL414482 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL266077 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL438580 | — | IC50 | = | 180.0 | nM | 6.75 |