Assay Detail
Binding
CHEMBL751226
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]nicotine binding to alpha4-beta2 nACh receptor from rat membranes from ref 14
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor; alpha4/beta2 (CHEMBL1907596) ↗| Type | PROTEIN COMPLEX |
| Organism | Rattus norvegicus |
Publication
Epibatidine structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 10.35 | 10.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298517 | (+)-EPIBATIDINE | — | 1 | 10.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298517 | (+)-EPIBATIDINE | Ki | = | 0.045 | nM | 10.35 |