Assay Detail
Functional
CHEMBL751256
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity against Opioid receptor delta 1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Design and parallel synthesis of piperidine libraries targeting the nociceptin (N/OFQ) receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.06 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111192 | — | — | 1 | 5.25 |
| CHEMBL109598 | — | — | 1 | 5.06 |
| CHEMBL322515 | — | — | 1 | 5.03 |
| CHEMBL112974 | — | — | 1 | 5.00 |
| CHEMBL111347 | — | — | 1 | 5.00 |
| CHEMBL111230 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111192 | — | Ki | = | 5674.0 | nM | 5.25 |
| CHEMBL109598 | — | Ki | = | 8779.0 | nM | 5.06 |
| CHEMBL322515 | — | Ki | = | 9385.0 | nM | 5.03 |
| CHEMBL112974 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL111347 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL111230 | — | Ki | = | 10000.0 | nM | 5.00 |