Assay Detail
Binding
CHEMBL751374
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against norepinephrine transporter
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Sodium-dependent noradrenaline transporter (CHEMBL222) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
From hit to lead. Analyzing structure-profile relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.67 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL116463 | — | — | 1 | 5.94 |
| CHEMBL115280 | — | — | 1 | 5.55 |
| CHEMBL115444 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL116463 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL115280 | — | IC50 | = | 2810.0 | nM | 5.55 |
| CHEMBL115444 | — | IC50 | = | 3020.0 | nM | 5.52 |