Assay Detail
Binding
CHEMBL751429
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of Nucleoside Triphosphate Diphosphohydrolase (NTPDase) from bovine spleen.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Spleen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Ectonucleoside triphosphate diphosphohydrolase 1 (CHEMBL2766) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Novel inhibitors of nucleoside triphosphate diphosphohydrolases: chemical synthesis and biochemical and pharmacological characterizations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.67 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2364580 | — | — | 1 | 5.00 |
| CHEMBL607720 | — | — | 1 | 4.80 |
| CHEMBL612159 | — | — | 1 | 4.51 |
| CHEMBL610939 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2364580 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL607720 | — | Ki | = | 16000.0 | nM | 4.80 |
| CHEMBL612159 | — | Ki | = | 31000.0 | nM | 4.51 |
| CHEMBL610939 | — | Ki | = | 45000.0 | nM | 4.35 |