Assay Detail
Binding
CHEMBL751610
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Binding affinity of compound to P-glycoprotein recombinant domain of prenylated xanthones was evaluated
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Prenylated xanthones as potential P-glycoprotein modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 10 | 5.76 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL26832 | — | — | 1 | 7.00 |
| CHEMBL26910 | — | — | 1 | 7.00 |
| CHEMBL27150 | — | — | 1 | 6.60 |
| CHEMBL25806 | — | — | 1 | 6.41 |
| CHEMBL26436 | — | — | 1 | 6.23 |
| CHEMBL27317 | — | — | 1 | 5.21 |
| CHEMBL27027 | — | — | 1 | 5.09 |
| CHEMBL27404 | — | — | 1 | 4.86 |
| CHEMBL281665 | — | — | 1 | 4.61 |
| CHEMBL26323 | DECUSSATIN | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL26832 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL26910 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL27150 | — | Kd | = | 250.0 | nM | 6.60 |
| CHEMBL25806 | — | Kd | = | 390.0 | nM | 6.41 |
| CHEMBL26436 | — | Kd | = | 590.0 | nM | 6.23 |
| CHEMBL27317 | — | Kd | = | 6100.0 | nM | 5.21 |
| CHEMBL27027 | — | Kd | = | 8050.0 | nM | 5.09 |
| CHEMBL27404 | — | Kd | = | 13900.0 | nM | 4.86 |
| CHEMBL281665 | — | Kd | = | 24800.0 | nM | 4.61 |
| CHEMBL26323 | DECUSSATIN | Kd | = | 28800.0 | nM | 4.54 |