Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL751787

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the inhibition of [125I]NKA binding to neurokinin NK2 receptor from hamster urinary bladder membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cricetulus griseus
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Substance-K receptor (CHEMBL2304405)
Type SINGLE PROTEIN
Organism Mesocricetus auratus

Publication

Pharmacological profile and chemical synthesis of SR 48968, a non-peptide antagonist of the neurokinin A (NK2) receptor
Emonds-Alt X, Proietto V, Van Broeck D, Vilain P, Advenier C, Neliat G, Le Fur G, Brelere J
Bioorg Med Chem Lett (1993) 3 : 925 -930
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.92 8.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL308148 SAREDUTANT 3.0 1 8.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL308148 SAREDUTANT Ki = 1.2 nM 8.92