Assay Detail
Binding
CHEMBL751913
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Binding affinity for nAChR with [3H]nicotine in rat brain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.68 | 7.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL149660 | — | — | 1 | 7.36 |
| CHEMBL97343 | 5-AZIDOIMIDACLOPRID | — | 1 | 7.36 |
| CHEMBL406819 | IMIDACLOPRID | — | 1 | 6.54 |
| CHEMBL148390 | — | — | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL149660 | — | Ki | = | 44.0 | nM | 7.36 |
| CHEMBL97343 | 5-AZIDOIMIDACLOPRID | Ki | = | 44.0 | nM | 7.36 |
| CHEMBL406819 | IMIDACLOPRID | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL148390 | — | Ki | = | 3500.0 | nM | 5.46 |