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Assay Detail

CHEMBL752057

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Binding
Tested for the inhibition of nitric oxide syntheses in murine macrophage cell line RAW 264.7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type RAW
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Two neolignans from Perilla frutescens and their inhibition of nitric oxide synthase and tumor necrosis factor-alpha expression in murine macrophage cell line RAW 264.7.
Ryu JH, Son HJ, Lee SH, Sohn DH.
Bioorg Med Chem Lett (2002) 12 : 649 -651
PubMed 11844692 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.27 4.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL156339 MAGNOSALIN 1 4.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL156339 MAGNOSALIN IC50 = 53500.0 nM 4.27