Assay Detail
Binding
CHEMBL752105
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory activity against opioid activity in guinea pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and opioid activity of dermorphin tetrapeptides bearing D-methionine S-oxide at position 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.16 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL172293 | — | — | 1 | 9.55 |
| CHEMBL170858 | — | — | 1 | 9.23 |
| CHEMBL170091 | — | — | 1 | 8.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL172293 | — | IC50 | = | 0.28 | nM | 9.55 |
| CHEMBL170858 | — | IC50 | = | 0.59 | nM | 9.23 |
| CHEMBL170091 | — | IC50 | = | 2.05 | nM | 8.69 |