Assay Detail
Binding
CHEMBL752129
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Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
[Pro(3)]Dyn A(1-11)-NH(2): a dynorphin analogue with high selectivity for the kappa opioid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.82 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL573214 | NORBINALTORPHIMINE | — | 1 | 7.72 |
| CHEMBL405190 | — | — | 1 | 6.39 |
| CHEMBL269377 | — | — | 1 | 5.41 |
| CHEMBL405097 | — | — | 1 | 5.17 |
| CHEMBL413729 | — | — | 1 | 5.15 |
| CHEMBL407389 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL573214 | NORBINALTORPHIMINE | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL405190 | — | Ki | = | 407.0 | nM | 6.39 |
| CHEMBL269377 | — | Ki | = | 3900.0 | nM | 5.41 |
| CHEMBL405097 | — | Ki | = | 6800.0 | nM | 5.17 |
| CHEMBL413729 | — | Ki | = | 7100.0 | nM | 5.15 |
| CHEMBL407389 | — | Ki | = | 8800.0 | nM | 5.06 |