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Assay Detail

CHEMBL752569

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of NRII and/or NRI phosphorylation in Escherichia coli
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities.
Sui Z, Guan J, Hlasta DJ, Macielag MJ, Foleno BD, Goldschmidt RM, Loeloff MJ, Webb GC, Barrett JF.
Bioorg Med Chem Lett (1998) 8 : 1929 -1934
PubMed 9873461 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.55 4.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL57037 1 4.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL57037 IC50 = 28000.0 nM 4.55