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Assay Detail

CHEMBL752717

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for NF-kappa B transcription factor of microvessel endothelial cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Cell Type Endothelial cell
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Nuclear factor NF-kappa-B complex (CHEMBL2094258)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Angiogenic factors: syntheses of 12(R)- and 12(S)-hydroxyeicosa-5(Z),8(Z),14(Z)-trienoic acid and their 14,15-dehydro analogs
Chauhan K, Ravi D, Falck J, Stoltz RA, Laniado-Schwartzman M
Bioorg Med Chem Lett (1994) 4 : 2689 -2692
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.37 10.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL329415 1 10.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL329415 Kd = 0.043 nM 10.37