Assay Detail
Binding
CHEMBL753049
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Hog kidney Na+, K+ -Dependent ATPase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cardiac glycosides. 1. A systematic study of digitoxigenin D-glycosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.52 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085490 | — | — | 1 | 8.15 |
| CHEMBL3349563 | — | — | 1 | 7.97 |
| CHEMBL2115218 | — | — | 1 | 7.93 |
| CHEMBL3349571 | — | — | 1 | 7.55 |
| CHEMBL3085489 | — | — | 1 | 7.38 |
| CHEMBL2114217 | — | — | 1 | 7.19 |
| CHEMBL3349581 | — | — | 1 | 7.03 |
| CHEMBL1453 | DIGITOXIGENIN | — | 1 | 6.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085490 | — | IC50 | = | 7.04 | nM | 8.15 |
| CHEMBL3349563 | — | IC50 | = | 10.7 | nM | 7.97 |
| CHEMBL2115218 | — | IC50 | = | 11.7 | nM | 7.93 |
| CHEMBL3349571 | — | IC50 | = | 28.2 | nM | 7.55 |
| CHEMBL3085489 | — | IC50 | = | 41.8 | nM | 7.38 |
| CHEMBL2114217 | — | IC50 | = | 64.5 | nM | 7.19 |
| CHEMBL3349581 | — | IC50 | = | 93.3 | nM | 7.03 |
| CHEMBL1453 | DIGITOXIGENIN | IC50 | = | 117.0 | nM | 6.93 |