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Assay Detail

CHEMBL753366

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The receptor binding activity as the displacement of specifically bound [3H]-NPY from male Sprague-Dawley rat brain membrane homogenates
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Brain
Subcellular Membrane
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Neuropeptide Y (NPY) functional group mimetics: design, synthesis, and characterization as NPY receptor antagonists
Doughty MB, Chu SS, Misse GA, Tessel R
Bioorg Med Chem Lett (1992) 2 : 1497 -1502
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.25 4.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19060 BENEXTRAMINE 1 4.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19060 BENEXTRAMINE IC50 = 56000.0 nM 4.25