Assay Detail
Binding
CHEMBL753367
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The receptor binding activity was evaluated as the displacement of specifically bound [3H]-NPY from male Sprague-Dawley rat brain membrane homogenates
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Neuropeptide Y (NPY) functional group mimetics: design, synthesis, and characterization as NPY receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.54 | 4.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290671 | — | — | 1 | 4.73 |
| CHEMBL35694 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290671 | — | IC50 | = | 18500.0 | nM | 4.73 |
| CHEMBL35694 | — | IC50 | = | 45400.0 | nM | 4.34 |