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Assay Detail

CHEMBL754064

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro growth inhibition of Plasmodium falciparum D6
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers.
Girault S, Grellier P, Berecibar A, Maes L, Lemière P, Mouray E, Davioud-Charvet E, Sergheraert C.
J Med Chem (2001) 44 : 1658 -1665
PubMed 11356101 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.13 7.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46736 1 7.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46736 IC50 = 74.5 nM 7.13