Assay Detail
Binding
CHEMBL754175
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Binding affinity to displace radioligand [3H]naltrindole on Opioid receptor delta 1 in guinea pig membranes.
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Selective protection and functionalization of morphine: synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 6.67 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL56585 | CYCLAZOCINE | 2.0 | 1 | 9.24 |
| CHEMBL2367916 | — | — | 1 | 8.28 |
| CHEMBL2367918 | — | — | 1 | 7.92 |
| CHEMBL70 | MORPHINE | 4.0 | 1 | 6.85 |
| CHEMBL333965 | — | — | 1 | 5.82 |
| CHEMBL119332 | — | — | 1 | 5.80 |
| CHEMBL333959 | — | — | 1 | 5.62 |
| CHEMBL332927 | — | — | 1 | 5.26 |
| CHEMBL119692 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL56585 | CYCLAZOCINE | Ki | = | 0.58 | nM | 9.24 |
| CHEMBL2367916 | — | Ki | = | 5.2 | nM | 8.28 |
| CHEMBL2367918 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL70 | MORPHINE | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL333965 | — | Ki | = | 1500.0 | nM | 5.82 |
| CHEMBL119332 | — | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL333959 | — | Ki | = | 2400.0 | nM | 5.62 |
| CHEMBL332927 | — | Ki | = | 5500.0 | nM | 5.26 |
| CHEMBL119692 | — | Ki | = | 5700.0 | nM | 5.24 |