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Assay Detail

CHEMBL754642

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the inhibition of inducible murine macrophage nitric oxide(NO) synthase, activity expressed as inhibitory constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

NG-allyl- and NG-cyclopropyl-L-arginine: two novel inhibitors of macrophage nitric oxide synthase.
Olken NM, Marletta MA.
J Med Chem (1992) 35 : 1137 -1144
PubMed 1372655 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.43 5.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL106425 5-N-ALLYL-ARGININE 1 5.47
CHEMBL256147 TILARGININE 3.0 1 5.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL106425 5-N-ALLYL-ARGININE Ki = 3400.0 nM 5.47
CHEMBL256147 TILARGININE Ki = 4200.0 nM 5.38