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Assay Detail

CHEMBL754788

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Equilibrium dissociation constant at human Neurotensin receptor (NT) receptor in NIE-115 neuroblastoma cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Neurotensin receptor (CHEMBL2111438)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Synthesis of partially non-peptidic neurotensin mimetics
Dood DS, Kozikowski AP, Cusack B, Richelson E
Bioorg Med Chem Lett (1994) 4 : 1241 -1246
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 5.60 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21448 1 5.72
CHEMBL265064 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21448 Kd = 1900.0 nM 5.72
CHEMBL265064 Kd = 3300.0 nM 5.48