Assay Detail
Binding
CHEMBL754789
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Binding ability to compete with [125I]Tyr3-NT (0.15 nM) for human NT receptors cloned in CHO cells.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Preparation and receptor binding affinities of cyclic C-terminal neurotensin (8-13) and (9-13) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.95 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48981 | — | — | 1 | 7.55 |
| CHEMBL1790704 | — | — | 1 | 6.35 |
| CHEMBL1790701 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48981 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL1790704 | — | Ki | = | 450.0 | nM | 6.35 |
| CHEMBL1790701 | — | Ki | > | 2000.0 | nM | - |