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Assay Detail

CHEMBL755133

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against neuronal nitric oxide synthase (nNOS)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Nitric oxide synthase 1 (CHEMBL3048)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.
Gómez-Vidal JA, Martásek P, Roman LJ, Silverman RB.
J Med Chem (2004) 47 : 703 -710
PubMed 14736250 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL44833 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL44833 Ki = 130.0 nM 6.89