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Assay Detail

CHEMBL755336

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Neuronal acetylcholine receptor; alpha4/beta2 (CHEMBL1907596)
Type PROTEIN COMPLEX
Organism Rattus norvegicus

Publication

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Holladay MW, Dart MJ, Lynch JK.
J Med Chem (1997) 40 : 4169 -4194
PubMed 9435889 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.32 7.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL25619 1 7.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL25619 EC50 = 48.0 nM 7.32