Assay Detail
Binding
CHEMBL755439
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Tested for binding affinity against delta1 opioid receptor using [3H]-DPDPE as a radioligand in the guinea pig brain membranes.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Electrophilic N-benzylnaltrindoles as delta opioid receptor-selective antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.02 | 10.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL282518 | — | — | 1 | 10.72 |
| CHEMBL26648 | — | — | 1 | 8.70 |
| CHEMBL280649 | — | — | 1 | 8.38 |
| CHEMBL282107 | — | — | 1 | 8.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL282518 | — | Ki | = | 0.019 | nM | 10.72 |
| CHEMBL26648 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL280649 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL282107 | — | Ki | = | 5.3 | nM | 8.28 |