Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL755693

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity at Opioid receptor kappa 1 by to cloned human opioid receptors expressed in CHO cell membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Kappa-type opioid receptor (CHEMBL237)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

[Pro(3)]Dyn A(1-11)-NH(2): a dynorphin analogue with high selectivity for the kappa opioid receptor.
Schlechtingen G, Zhang L, Maycock A, DeHaven RN, Daubert JD, Cassel J, Chung NN, Schiller PW, Goodman M.
J Med Chem (2000) 43 : 2698 -2702
PubMed 10893307 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.12 8.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL407389 1 8.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL407389 Ki = 7.5 nM 8.12