Assay Detail
Binding
CHEMBL756186
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In vitro binding affinity towards opioid receptor delta 1
46
Total Activities
46
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, micro and delta opioid agonists: a micro address.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 46 | 8.04 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL68412 | — | — | 1 | 9.82 |
| CHEMBL302801 | — | — | 1 | 9.62 |
| CHEMBL67790 | — | — | 1 | 9.60 |
| CHEMBL434018 | — | — | 1 | 9.42 |
| CHEMBL66741 | — | — | 1 | 9.29 |
| CHEMBL67240 | — | — | 1 | 9.14 |
| CHEMBL291357 | — | — | 1 | 9.07 |
| CHEMBL63232 | — | — | 1 | 9.03 |
| CHEMBL67326 | — | — | 1 | 8.88 |
| CHEMBL303875 | — | — | 1 | 8.84 |
| CHEMBL65259 | — | — | 1 | 8.70 |
| CHEMBL433500 | — | — | 1 | 8.68 |
| CHEMBL68342 | — | — | 1 | 8.65 |
| CHEMBL416680 | — | — | 1 | 8.41 |
| CHEMBL419621 | — | — | 1 | 8.38 |
| CHEMBL63912 | — | — | 1 | 8.35 |
| CHEMBL66954 | — | — | 1 | 8.33 |
| CHEMBL307525 | — | — | 1 | 8.26 |
| CHEMBL279638 | — | — | 1 | 8.25 |
| CHEMBL67893 | — | — | 1 | 8.19 |
| CHEMBL304214 | — | — | 1 | 8.18 |
| CHEMBL303381 | — | — | 1 | 8.11 |
| CHEMBL302142 | — | — | 1 | 8.11 |
| CHEMBL67123 | — | — | 1 | 7.95 |
| CHEMBL67894 | — | — | 1 | 7.91 |
| CHEMBL63309 | — | — | 1 | 7.89 |
| CHEMBL64933 | — | — | 1 | 7.88 |
| CHEMBL306463 | — | — | 1 | 7.80 |
| CHEMBL307973 | — | — | 1 | 7.70 |
| CHEMBL67289 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL68412 | — | Ki | = | 0.152 | nM | 9.82 |
| CHEMBL302801 | — | Ki | = | 0.24 | nM | 9.62 |
| CHEMBL67790 | — | Ki | = | 0.25 | nM | 9.60 |
| CHEMBL434018 | — | Ki | = | 0.384 | nM | 9.42 |
| CHEMBL66741 | — | Ki | = | 0.51 | nM | 9.29 |
| CHEMBL67240 | — | Ki | = | 0.72 | nM | 9.14 |
| CHEMBL291357 | — | Ki | = | 0.86 | nM | 9.07 |
| CHEMBL63232 | — | Ki | = | 0.93 | nM | 9.03 |
| CHEMBL67326 | — | Ki | = | 1.32 | nM | 8.88 |
| CHEMBL303875 | — | Ki | = | 1.45 | nM | 8.84 |
| CHEMBL65259 | — | Ki | = | 2.02 | nM | 8.70 |
| CHEMBL433500 | — | Ki | = | 2.09 | nM | 8.68 |
| CHEMBL68342 | — | Ki | = | 2.24 | nM | 8.65 |
| CHEMBL416680 | — | Ki | = | 3.88 | nM | 8.41 |
| CHEMBL419621 | — | Ki | = | 4.14 | nM | 8.38 |
| CHEMBL63912 | — | Ki | = | 4.5 | nM | 8.35 |
| CHEMBL66954 | — | Ki | = | 4.69 | nM | 8.33 |
| CHEMBL307525 | — | Ki | = | 5.48 | nM | 8.26 |
| CHEMBL279638 | — | Ki | = | 5.67 | nM | 8.25 |
| CHEMBL67893 | — | Ki | = | 6.39 | nM | 8.19 |
| CHEMBL304214 | — | Ki | = | 6.66 | nM | 8.18 |
| CHEMBL303381 | — | Ki | = | 7.8 | nM | 8.11 |
| CHEMBL302142 | — | Ki | = | 7.72 | nM | 8.11 |
| CHEMBL67123 | — | Ki | = | 11.29 | nM | 7.95 |
| CHEMBL67894 | — | Ki | = | 12.3 | nM | 7.91 |
| CHEMBL63309 | — | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL64933 | — | Ki | = | 13.16 | nM | 7.88 |
| CHEMBL306463 | — | Ki | = | 15.9 | nM | 7.80 |
| CHEMBL307973 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL67289 | — | Ki | = | 19.79 | nM | 7.70 |
| CHEMBL63563 | — | Ki | = | 20.77 | nM | 7.68 |
| CHEMBL67615 | — | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL66800 | — | Ki | = | 23.7 | nM | 7.62 |
| CHEMBL292332 | — | Ki | = | 26.17 | nM | 7.58 |
| CHEMBL67735 | — | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL66955 | — | Ki | = | 35.9 | nM | 7.45 |
| CHEMBL68113 | — | Ki | = | 42.1 | nM | 7.38 |
| CHEMBL63651 | — | Ki | = | 46.7 | nM | 7.33 |
| CHEMBL68358 | — | Ki | = | 49.3 | nM | 7.31 |
| CHEMBL67428 | — | Ki | = | 49.53 | nM | 7.30 |
| CHEMBL67088 | — | Ki | = | 63.4 | nM | 7.20 |
| CHEMBL67144 | — | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL68341 | — | Ki | = | 292.0 | nM | 6.54 |
| CHEMBL67781 | — | Ki | = | 352.0 | nM | 6.45 |
| CHEMBL303148 | — | Ki | = | 924.0 | nM | 6.03 |
| CHEMBL304466 | — | Ki | = | 1517.0 | nM | 5.82 |