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Assay Detail

CHEMBL756290

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was evaluated for antagonist activity against platelet P2Y purinoceptor 12 (P2Y12)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

P2Y purinoceptor 12 (CHEMBL2001)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Purine and pyrimidine (P2) receptors as drug targets.
Jacobson KA, Jarvis MF, Williams M.
J Med Chem (2002) 45 : 4057 -4093
PubMed 12213051 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL334966 CANGRELOR 4.0 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL334966 CANGRELOR IC50 = 0.4 nM 9.40