Assay Detail
Functional
CHEMBL756492
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDJ-2 farnesylation in PSN-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PSN-1 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.93 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL354677 | — | — | 1 | 5.97 |
| CHEMBL355551 | — | — | 1 | 5.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL354677 | — | EC50 | = | 1064.0 | nM | 5.97 |
| CHEMBL355551 | — | EC50 | = | 1332.0 | nM | 5.88 |