Assay Detail
Binding
CHEMBL756501
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Inhibition of protein-tyrosine kinase p56lck
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Hydroxylated 2-(5'-salicyl)naphthalenes as protein-tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.20 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL102362 | — | — | 1 | 7.22 |
| CHEMBL319620 | LAVENDUSTIN C | — | 1 | 5.00 |
| CHEMBL103960 | — | — | 1 | 4.38 |
| CHEMBL100446 | — | — | 1 | 4.19 |
| CHEMBL102336 | — | — | 1 | - |
| CHEMBL103684 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL102362 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL319620 | LAVENDUSTIN C | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL103960 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL100446 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL102336 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL103684 | — | IC50 | = | 150000.0 | nM | - |