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Assay Detail

CHEMBL756939

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Canine Tracheal Smooth Muscle PDE 4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canis lupus familiaris
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Phosphodiesterase 4 (CHEMBL2093863)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.
Suzuki F, Kuroda T, Kawakita T, Manabe H, Kitamura S, Ohmori K, Ichimura M, Kase H, Ichikawa S.
J Med Chem (1992) 35 : 4866 -4874
PubMed 1479586 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.92 4.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95509 1 4.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95509 IC50 = 12000.0 nM 4.92