Assay Detail
Binding
CHEMBL757025
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Compound was evaluated for the ability to inhibit penicillopepsin.
8
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 7.45 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296588 | PEPSTATIN | 2.0 | 1 | 9.82 |
| CHEMBL330017 | — | — | 1 | 9.40 |
| CHEMBL432824 | — | — | 1 | 7.33 |
| CHEMBL120764 | — | — | 2 | 7.10 |
| CHEMBL314751 | — | — | 1 | 7.07 |
| CHEMBL315875 | — | — | 1 | 6.30 |
| CHEMBL433370 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296588 | PEPSTATIN | Ki | = | 0.15 | nM | 9.82 |
| CHEMBL330017 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL432824 | — | Ki | = | 47.0 | nM | 7.33 |
| CHEMBL120764 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL314751 | — | Ki | = | 85.0 | nM | 7.07 |
| CHEMBL315875 | — | Ki | = | 500.0 | nM | 6.30 |
| CHEMBL433370 | — | Ki | = | 7600.0 | nM | 5.12 |
| CHEMBL120764 | — | Ki | > | 5000.0 | nM | - |