Assay Detail
Binding
CHEMBL757028
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Compound was tested for inhibition of Rhizopus chinensis pepsin.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rosa chinensis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.52 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3142508 | — | — | 1 | 8.14 |
| CHEMBL3142505 | — | — | 1 | 8.04 |
| CHEMBL3142513 | — | — | 1 | 7.85 |
| CHEMBL3142507 | — | — | 1 | 7.29 |
| CHEMBL3142506 | — | — | 1 | 7.11 |
| CHEMBL3142509 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3142508 | — | Ki | = | 7.2 | nM | 8.14 |
| CHEMBL3142505 | — | Ki | = | 9.2 | nM | 8.04 |
| CHEMBL3142513 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL3142507 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL3142506 | — | Ki | = | 78.0 | nM | 7.11 |
| CHEMBL3142509 | — | Ki | = | 210.0 | nM | 6.68 |