Assay Detail
Binding
CHEMBL757141
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Inhibition of cAMP-dependent protein kinase (PKA)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
cAMP-dependent protein kinase (PKA) (CHEMBL2094138) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Synthesis and protein kinase C inhibitory activities of indane analogs of balanol
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.82 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL427118 | — | — | 1 | 7.52 |
| CHEMBL177635 | — | — | 1 | 7.16 |
| CHEMBL177308 | — | — | 1 | 4.30 |
| CHEMBL367127 | — | — | 1 | 4.30 |
| CHEMBL367457 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL427118 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL177635 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL177308 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL367127 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL367457 | — | IC50 | > | 100000.0 | nM | - |