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Assay Detail

CHEMBL757546

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Functional
In vitro evaluation for the inhibitory activity against drug sensitive P388 cells (P388/S) cells at a concentration of 5.0 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388/S
Confidence 1 — Organism
Curated By Intermediate

Target

P388/S (CHEMBL614220)
Type CELL-LINE
Organism Mus musculus

Publication

Novel inhibitors for multidrug resistance: 1,3,5-triazacycloheptanes.
Sawanishi H, Wakusawa S, Murakami R, Muramatsu H, Suzuki H, Takashima A, Aizawa T, Miyamoto K.
J Med Chem (1995) 38 : 5066 -5070
PubMed 8544183 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL268154 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL268154 IC50 = 0.4 nM 9.40