Assay Detail
Binding
CHEMBL758011
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of Penicillin-binding protein 2x from Streptococcus pneumoniae
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Streptococcus pneumoniae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.99 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121924 | — | — | 1 | 5.35 |
| CHEMBL332565 | — | — | 1 | 5.32 |
| CHEMBL333330 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121924 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL332565 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL333330 | — | IC50 | = | 50000.0 | nM | 4.30 |