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Assay Detail

CHEMBL758137

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the growth inhibition of P388/S cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388/S
Confidence 1 — Organism
Curated By Intermediate

Target

P388/S (CHEMBL614220)
Type CELL-LINE
Organism Mus musculus

Publication

N-(2-hydroxyethyl)doxorubicin from hydrolysis of 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin.
Acton EM, Tong GL, Smith TH, Taylor DL, Streeter DG, Peters JH, Gordon GR, Filppi JA, Wolgemuth RL, Giuliani FC.
J Med Chem (1986) 29 : 2120 -2122
PubMed 3761328 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.80 9.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278828 1 9.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278828 IC50 = 0.16 nM 9.80