Assay Detail
Functional
CHEMBL759190
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro stimulation of 2PY1 purinoceptor mediated phospholipase C (PLC) activity in Turkey Erythrocyte Ghosts
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Meleagris gallopavo |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.15 | 6.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL353178 | — | — | 1 | 6.81 |
| CHEMBL607338 | — | — | 1 | 5.52 |
| CHEMBL355406 | — | — | 1 | 5.19 |
| CHEMBL165225 | — | — | 1 | 5.14 |
| CHEMBL166163 | — | — | 1 | 5.03 |
| CHEMBL444868 | — | — | 1 | 4.72 |
| CHEMBL352431 | — | — | 1 | 4.43 |
| CHEMBL169580 | — | — | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL353178 | — | EC50 | = | 155.0 | nM | 6.81 |
| CHEMBL607338 | — | EC50 | = | 2990.0 | nM | 5.52 |
| CHEMBL355406 | — | EC50 | = | 6510.0 | nM | 5.19 |
| CHEMBL165225 | — | EC50 | = | 7210.0 | nM | 5.14 |
| CHEMBL166163 | — | EC50 | = | 9350.0 | nM | 5.03 |
| CHEMBL444868 | — | EC50 | = | 18900.0 | nM | 4.72 |
| CHEMBL352431 | — | EC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL169580 | — | EC50 | = | 41000.0 | nM | 4.39 |