Assay Detail
Functional
CHEMBL759191
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity against Turkey erythrocyte P2Y purinoceptor 1 (P2Y1) by the compound is measured
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Meleagris gallopavo |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.99 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085531 | — | — | 1 | 7.28 |
| CHEMBL403456 | — | — | 1 | 6.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085531 | — | IC50 | = | 52.0 | nM | 7.28 |
| CHEMBL403456 | — | IC50 | = | 206.0 | nM | 6.69 |