Assay Detail
Binding
CHEMBL759405
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In vitro binding affinity against human Peroxisome proliferator activated receptor delta
17
Total Activities
17
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
5-aryl thiazolidine-2,4-diones: discovery of PPAR dual alpha/gamma agonists as antidiabetic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 17 | 5.89 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96107 | — | — | 1 | 6.72 |
| CHEMBL330191 | — | — | 1 | 5.52 |
| CHEMBL94397 | — | — | 1 | 5.42 |
| CHEMBL94496 | — | — | 1 | - |
| CHEMBL420441 | — | — | 1 | - |
| CHEMBL121 | ROSIGLITAZONE | 4.0 | 1 | - |
| CHEMBL300629 | — | — | 1 | - |
| CHEMBL328615 | — | — | 1 | - |
| CHEMBL97529 | — | — | 1 | - |
| CHEMBL96758 | — | — | 1 | - |
| CHEMBL96143 | — | — | 1 | - |
| CHEMBL94716 | — | — | 1 | - |
| CHEMBL96451 | — | — | 1 | - |
| CHEMBL92130 | — | — | 1 | - |
| CHEMBL318684 | — | — | 1 | - |
| CHEMBL327767 | — | — | 1 | - |
| CHEMBL94306 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96107 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL330191 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL94397 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL94496 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL420441 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL121 | ROSIGLITAZONE | IC50 | > | 50000.0 | nM | - |
| CHEMBL300629 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL328615 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL97529 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL96758 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL96143 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL94716 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL96451 | — | IC50 | > | 5000.0 | nM | - |
| CHEMBL92130 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL318684 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL327767 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL94306 | — | IC50 | > | 10000.0 | nM | - |