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Assay Detail

CHEMBL759456

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration of the PPAR gamma)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Peroxisome proliferator-activated receptor gamma (CHEMBL235)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological activity of a novel series of indole-derived PPARgamma agonists.
Henke BR, Adkison KK, Blanchard SG, Leesnitzer LM, Mook RA, Plunket KD, Ray JA, Roberson C, Unwalla R, Willson TM.
Bioorg Med Chem Lett (1999) 9 : 3329 -3334
PubMed 10612594 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL320553 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL320553 IC50 = 50.0 nM 7.30