Assay Detail
Functional
CHEMBL759513
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The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Purine and pyrimidine (P2) receptors as drug targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.91 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1628528 | — | — | 1 | 8.82 |
| CHEMBL131091 | — | — | 1 | 7.85 |
| CHEMBL69727 | ISOPPADS | — | 1 | 7.37 |
| CHEMBL82202 | PYRIDOXAL PHOSPHATE ANHYDROUS | 3.0 | 1 | 5.52 |
| CHEMBL74121 | — | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1628528 | — | EC50 | = | 1.5 | nM | 8.82 |
| CHEMBL131091 | — | EC50 | = | 14.0 | nM | 7.85 |
| CHEMBL69727 | ISOPPADS | EC50 | = | 43.0 | nM | 7.37 |
| CHEMBL82202 | PYRIDOXAL PHOSPHATE ANHYDROUS | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL74121 | — | EC50 | = | 10200.0 | nM | 4.99 |