Assay Detail
Functional
CHEMBL759514
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The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Oocyte |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Purine and pyrimidine (P2) receptors as drug targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.52 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL337062 | — | — | 1 | 7.01 |
| CHEMBL69234 | — | — | 1 | 7.00 |
| CHEMBL130094 | — | — | 1 | 6.08 |
| CHEMBL265502 | SURAMIN | 3.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL337062 | — | EC50 | = | 98.0 | nM | 7.01 |
| CHEMBL69234 | — | EC50 | = | 99.0 | nM | 7.00 |
| CHEMBL130094 | — | EC50 | = | 840.0 | nM | 6.08 |
| CHEMBL265502 | SURAMIN | EC50 | = | 1000.0 | nM | 6.00 |