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Assay Detail

CHEMBL759515

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferens
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

P2X purinoceptor 1 (CHEMBL2530)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Purine and pyrimidine (P2) receptors as drug targets.
Jacobson KA, Jarvis MF, Williams M.
J Med Chem (2002) 45 : 4057 -4093
PubMed 12213051 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.07 5.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL130059 UNIBLUE A 1 5.12
CHEMBL134193 CIBACRON BLUE 3GA 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL130059 UNIBLUE A IC50 = 7500.0 nM 5.12
CHEMBL134193 CIBACRON BLUE 3GA IC50 = 9600.0 nM 5.02